Parkinson Platform Noord Nederland

We read with interest the Article by Marialuisa Quadri and colleagues1 in The Lancet Neurology, in which they suggested LRP10 mutations as a cause of Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies. As part of the International Parkinson's Disease Genomics Consortium, we analysed LRP10 in exome sequencing data from 2835 individuals with Parksinson's disease and 5343 individuals without known neurological disease (appendix). We also analysed exome sequencing data from 111 individuals with pathologically confirmed dementia with Lewy bodies and another 233 individuals without known neurological disease (appendix).