15Dec

[Comment] Subthalamotomy for Parkinson’s disease: back to the future?

MRI-guided focused ultrasound is a novel method for creating thermic ablations in the thalamus or basal ganglia without opening the skull. The method uses focused sonic energy and real-time MRI thermography of brain temperature to control lesion size and location precisely. This is a principle advantage over gamma-knife radiosurgery, which is another incision-free lesioning technique but induces radionecrosis that is difficult to control and develops within months of the procedure. In July, 2016, the US Food and Drug Administration approved MRI-guided focused ultrasound for unilateral thalamotomy for treatment of medically refractory and disabling essential tremor.

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20May

[Comment] A new step towards targeting tau

Progressive supranuclear palsy is a rare neurodegenerative disease characterised by an axial parkins...

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20May

[Review] CSF and blood biomarkers for Parkinson’s disease

In the management of Parkinson's disease, reliable diagnostic and prognostic biomarkers are urg...

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22Apr

Parkinson’s disease patient: ‘I can walk… it’s really helped me’

Parkinson's disease patient Gail Jardine can walk more freely after having a spinal implant fit...

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