Parkinson Platform Noord Nederland

Chromosome 22q11.2 deletion syndrome is a group of heterogeneous disorders characterised by a deletion near the middle of chromosome 22 at a location designated q11.2. The clinical phenotype varies widely, with multiple system involvement. Well-recognised features include cleft palate, dysmorphic facial features, cardiac defects, skeletal deformities, developmental delays, and learning disabilities.1 Many affected people are identified at a young age. These patients are at an increased risk of developing schizophrenia and other mental disorders, and have a reduced lifespan.