Parkinson Platform Noord Nederland

A major challenge to patients, clinicians, family members, and scientists is the unpredictable future that accompanies a diagnosis of Parkinson's disease. When met with the question “what does my future hold?” it is difficult to give predictions that are likely to be useful to the patient. Some individuals will face features that rapidly and adversely affect their quality of life; others will experience a prolonged and fairly benign course, initially well managed by drugs and lifestyle changes. Variability between patients in core features of this multisystem disease—eg, motor decline, neuropsychiatric changes, mood disorders, dysautonomic signs, and fatigue—is the rule.