The changing tree in Parkinson’s disease

Nature Neuroscience 18, 1196 (2015).

Authors: Paolo Calabresi & Massimiliano Di Filippo

Dopamine loss in Parkinson's disease affects not only the basal ganglia, but also motor cortex, causing a surprising increase of spine turnover in the cortical dendritic tree and altering synaptic plasticity and memory retention.

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